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M4 mAChR Modulator-1
M4 mAChR Modulator-1
SKU:QM-0114744
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Quantity
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Product Details
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Description
M4 mAChR Modulator-1 (compound 23i) is a M4 mAChR positive allosteric modulator (PAM) . M4 mAChR Modulator-1 exhibits significantly greater cooperativity with ACh in β-arrestin recruitment over G protein activation. M4 mAChR Modulator-1 displays weak PAM effect in G protein-mediated responses, but strong PAM effect in β-arrestin recruitment[1].
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Molecular Formula
C22H23N5O
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Molecular Weight
373.45
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Smiles
O=C1NCC2=C1C=C(C3=NC(C)=NC=C3C4=CN(CC5CCCC5)N=C4)C=C2
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Target
MAChR
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Isoform
MAChR4
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Shipping Conditions
Room temperature
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M4 mAChR Modulator-1
M4 mAChR Modulator-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.