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MGluR2 modulator 5 [CAS 1639898-35-3]
MGluR2 modulator 5 [CAS 1639898-35-3]
SKU:QM-0118356
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Product Details
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Description
MGluR2 modulator 5 (Compound 11) is an orally active, selective mGluR2 negative allosteric modulator with an IC50 of 8.9 nM. Pharmacokinetic studies in rats show that mGluR2 modulator 5 can effectively cross the blood-brain barrier. It can modulate cognitive and neurological functions in mood disorders and is suitable for research in the field of neurodegenerative diseases[1].
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CAS Number
[1639898-35-3]
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Molecular Formula
C20H17F3N4O
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Molecular Weight
386.37
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Smiles
CC1=NC=CC(C2=C(C(N(C3=CC=C(C(F)(F)F)C=C3)C[C@@H]4C)=O)N4N=C2)=C1
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Target
MGluR
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Isoform
MGluR2
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Shipping Conditions
Room temperature
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MGluR2 modulator 5 [CAS 1639898-35-3]
MGluR2 modulator 5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.