MKK7-JNK activator 1 [CAS 3100092-62-1]
MKK7-JNK activator 1 [CAS 3100092-62-1]
SKU:QM-0015687
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Product Details
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Description
MKK7-JNK activator 1 (Compound 10) is a MKK7-JNK pathway activator. MKK7-JNK activator 1 effectively inhibits the proliferation and migration of MDA-MB-468 cells, induces G2/M phase arrest and caspase -dependent apoptosis (independent of ROS production) . MKK7-JNK activator 1 significantly increases the levels of p-MKK7 and p-JNK, but does not affect p-ERK or p-p38. MKK7-JNK activator 1 can be used for the study of triple-negative breast cancer (TNBC) [1].
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CAS Number
[3100092-62-1]
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Molecular Formula
C17H12Br2INO
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Molecular Weight
533
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Smiles
CC1=NC2=C(OCC3=CC=CC(I)=C3)C(Br)=CC(Br)=C2C=C1
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Target
Apoptosis; Caspase; JNK; p38 MAPK
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Isoform
Caspase 3; Caspase 8; Caspase 9
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Shipping Conditions
Room temperature
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MKK7-JNK activator 1 [CAS 3100092-62-1]
MKK7-JNK activator 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.