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MRGPRX4 modulator-3
MRGPRX4 modulator-3
SKU:QM-0013339
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Product Details
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Description
MRGPRX4 modulator-3 (Compound 1C) is a negative allosteric MAS-related G-protein-coupled receptor X4 (MRGPRX4) modulator. MRGPRX4 modulator-3 significantly attenuates Nateglinide (orthosteric agonist) -induced responses with an IC50 of 337 nM. MRGPRX4 modulator-3 can be used for chronic itch (especially cholestatic itch) and pain research[1].
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Molecular Formula
C19H22FN3S
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Molecular Weight
343.46
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Smiles
C[C@]1(C2(C)C)/C(C[C@@H]2CC1)=N\NC3=NC(C4=CC=C(F)C=C4)=CS3
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Target
Mas-related G-protein-coupled Receptor (MRGPR)
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Shipping Conditions
Room temperature
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MRGPRX4 modulator-3
MRGPRX4 modulator-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.