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Mu opioid receptor antagonist 3 [CAS 2773925-66-7]

Mu opioid receptor antagonist 3 [CAS 2773925-66-7]

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SKU:QM-0065886

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  • Description

    Mu opioid receptor antagonist 3 (compound 26) is a potent and selective μ opioid receptor (MOR) antagonist with a Ki of 0.24 nM and an EC50 of 0.54 nM. Mu opioid receptor antagonist 3 has remarkable CNS antagonism against morphine, and precipitated fewer withdrawal symptoms than Naloxone. Mu opioid receptor antagonist 3 can be used for researching opioid use disorders (OUD) [1].

  • CAS Number

    [2773925-66-7]

  • Molecular Formula

    C25H28N2O4S

  • Molecular Weight

    452.57

  • Smiles

    O[C@]12[C@H]3CC4=C5[C@@]1(CCN3CC6CC6)[C@H]([C@@H](CC2)NC(C7=CC=CS7)=O)OC5=C(O)C=C4

  • Target

    Opioid Receptor

  • Isoform

    μ Opioid Receptor/MOR

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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Mu opioid receptor antagonist 3 [CAS 2773925-66-7]

Mu opioid receptor antagonist 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.