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Multi-target kinase inhibitor 2

Multi-target kinase inhibitor 2

Size

QM-0150102-01

£135.25 GBP
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Product Details

  • Description

    Multi-target kinase inhibitor 2 is a multi-targeted kinase inhibitor, and exhibits activity against EGFR, Her2, VEGFR2, and CDK2 enzymes, with IC50 values of 79 nM, 40 nM,136 nM, and 204 nM, respectively. Multi-target kinase inhibitor 2 shows cytotoxic effects were observed against HepG2, HeLa , MDA-MB-231 and MCF-7, with IC50 of 41, 57, 51 and 59 μM. Multi-target kinase inhibitor 2 induces cell cycle arrest and apoptosis in HepG2 cells[1].

  • Molecular Formula

    C20H14Cl2N6O

  • Molecular Weight

    425.27

  • Smiles

    O=C(N/N=C/C1=CC(Cl)=C(Cl)C=C1)C2=CC=C(C=C2)NC3=NC=NC4=C3C=CN4

  • Target

    Apoptosis; CDK; EGFR; VEGFR

  • Isoform

    CDK2; EGFR/ErbB1/HER1; ErbB2/HER2; VEGFR2/KDR/Flk-1

  • Purity

    99.82

  • Solubility

    DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice
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Variant Variant total Quantity Price Variant total
5 mgQM-0150102-01
5 mgQM-0150102-01
£135.25/ea		 £0.00
£135.25/ea £0.00
10 mgQM-0150102-02
10 mgQM-0150102-02
£238.32/ea		 £0.00
£238.32/ea £0.00
25 mgQM-0150102-03
25 mgQM-0150102-03
£426.65/ea		 £0.00
£426.65/ea £0.00
50 mgQM-0150102-04
50 mgQM-0150102-04
£652.64/ea		 £0.00
£652.64/ea £0.00
100 mgQM-0150102-05
100 mgQM-0150102-05
£1,015.92/ea		 £0.00
£1,015.92/ea £0.00
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Multi-target kinase inhibitor 2

Multi-target kinase inhibitor 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.