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Mutant EGFR inhibitor [CAS 1421373-62-7]
Mutant EGFR inhibitor [CAS 1421373-62-7]
SKU:QM-0146881-01
£238.32 GBP
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Product Details
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Description
Mutant EGFR inhibitor (Example 25) is a potent mutant EGFR inhibitor. Mutant EGFR inhibitor inhibits FGFRWT with an IC50 of 0.41 nM. Mutant EGFR inhibitor inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M. Mutant EGFR inhibitor can be used for the study of diseases mediated by EGFR (particularly cancers) [1].
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CAS Number
[1421373-62-7]
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Molecular Formula
C27H30ClN7O2
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Molecular Weight
520.03
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Smiles
C=CC(NC1=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O
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Target
EGFR
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Isoform
EGFR/ErbB1/HER1
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Purity
99.4
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Solubility
DMSO : ≥ 50 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Mutant EGFR inhibitor [CAS 1421373-62-7]
Mutant EGFR inhibitor is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.