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NAChR agonist 1 [CAS 1394371-75-5]

NAChR agonist 1 [CAS 1394371-75-5]

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QM-0144265-01

£514.13 GBP
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Product Details

  • Description

    NAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR) . nAChR agonist 1 has the EC50 of 0.32 μM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease[1].

  • CAS Number

    [1394371-75-5]

  • Molecular Formula

    C20H18ClNO3S2

  • Molecular Weight

    419.94

  • Smiles

    NS(C1=CC=C(C2=C(C(CC)=O)SC(C3=CC=C(Cl)C=C3)=C2C)C=C1)(=O)=O

  • Target

    NAChR

  • Purity

    98.35

  • Solubility

    DMSO : 125 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Variant Variant total Quantity Price Variant total
5 mgQM-0144265-01
5 mgQM-0144265-01
£514.13/ea		 £0.00
£514.13/ea £0.00
10 mM - 1 mLQM-0144265-02
10 mM - 1 mLQM-0144265-02
£560.30/ea		 £0.00
£560.30/ea £0.00
10 mgQM-0144265-03
10 mgQM-0144265-03
£740.12/ea		 £0.00
£740.12/ea £0.00
25 mgQM-0144265-04
25 mgQM-0144265-04
£1,179.95/ea		 £0.00
£1,179.95/ea £0.00
50 mgQM-0144265-05
50 mgQM-0144265-05
£1,580.90/ea		 £0.00
£1,580.90/ea £0.00
100 mgQM-0144265-06
100 mgQM-0144265-06
£2,121.57/ea		 £0.00
£2,121.57/ea £0.00
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NAChR agonist 1 [CAS 1394371-75-5]

NAChR agonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.