NAMPT activator-6 [CAS 2237267-86-4]
NAMPT activator-6 [CAS 2237267-86-4]
SKU:QM-0133310
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Product Details
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Description
NAMPT activator-6 is a NAMPT activator, a regulatory molecule for the optical control system of NAMPT and NAD+. NAMPT activator-6 can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) to achieve up-down reversible regulation of NAMPT and NAD+ in a light-dependent manner and reduce the toxicity associated with inhibitor-based PS-PROTACs. PS-PROTAC can be used to achieve antitumor activity, NAMPT, and NAD+ modulation in vivo via optical manipulation[1].
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CAS Number
[2237267-86-4]
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Molecular Formula
C17H21N5O3S
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Molecular Weight
375.45
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Smiles
O=C(NCC1=CC=NC=C1)NC2=CC=C(S(=O)(N3CCNCC3)=O)C=C2
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Target
NAMPT
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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NAMPT activator-6 [CAS 2237267-86-4]
NAMPT activator-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.