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NLRP3 agonist 1 [CAS 2454019-69-1]
NLRP3 agonist 1 [CAS 2454019-69-1]
SKU:QM-0151963-01
£740.12 GBP
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Product Details
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Description
NLRP3 agonist 1 (Compound 23) is an orally active NLRP3 agonist. NLRP3 agonist 1 can activate the enzyme Caspase-1 to cleave pro-IL-1β and pro-IL-18 proinflammatory cytokines into their mature forms[1].
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CAS Number
[2454019-69-1]
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Molecular Formula
C15H16N6
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Molecular Weight
280.33
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Smiles
NC1=NC(NC2(C)CC2)=C3C(C=C(C=C3)C4=NNC=C4)=N1
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Target
Caspase; NOD-like Receptor (NLR)
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Isoform
Caspase 1
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Purity
99.47
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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NLRP3 agonist 1 [CAS 2454019-69-1]
NLRP3 agonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.