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NOD1/2 antagonist-1 [CAS 2704623-69-6]
NOD1/2 antagonist-1 [CAS 2704623-69-6]
SKU:QM-0066532
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Product Details
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Description
NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding oligomerization domain-like receptor 1/2) dual antagonist, with IC50 values of 1.13 (NOD1) and 0.77 μM (NOD2), respectively. NOD1/2 antagonist-1 has a acceptable T1/2 (67.6 min) . NOD1/2 antagonist-1 (compound 36b) can improve the antitumor efficacy of Paclitaxel (PTX) [1].
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CAS Number
[2704623-69-6]
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Molecular Formula
C32H28ClF5N4O4
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Molecular Weight
663.03
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Smiles
O=C(C1=C(C=C2C(N(C=NC2=C1)CC(N3CCCC(F)(C3)F)=O)=O)C4=CC(Cl)=CC=C4)NCCCOC5=CC=C(C=C5)C(F)(F)F
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Target
NOD-like Receptor (NLR)
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Isoform
NOD1; NOD2
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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NOD1/2 antagonist-1 [CAS 2704623-69-6]
NOD1/2 antagonist-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.