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NOD1/2 antagonist-2 [CAS 2101736-25-6]
NOD1/2 antagonist-2 [CAS 2101736-25-6]
SKU:QM-0002515
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Product Details
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Description
NOD1/2 antagonist-2 (Compound 26BH) is a dual NOD1/NOD2 antagonist (IC50s: 2.36 μM and 4.16 μM for NOD1 and NOD2, respectively). NOD1/2 antagonist-2 inhibits both NF-κB and MAPK inflammatory signaling, thereby sensitizing Paclitaxel to suppress Lewis lung carcinoma growth[1].
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CAS Number
[2101736-25-6]
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Molecular Formula
C32H37N5O6
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Molecular Weight
587.67
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Smiles
O=C(C1=CC(OC2=CC=CC(N(C)C)=C2)=C(NC(COCC3=CC=CC=C3)=O)C=C1N4)N[C@H](CCC(NCCC)=O)C4=O
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Target
NOD-like Receptor (NLR)
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Isoform
NOD1; NOD2
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Shipping Conditions
Room temperature
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NOD1/2 antagonist-2 [CAS 2101736-25-6]
NOD1/2 antagonist-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.