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NOD2 antagonist 1 [CAS 2411441-54-6]
NOD2 antagonist 1 [CAS 2411441-54-6]
SKU:QM-0149411-01
£288.14 GBP
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Product Details
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Description
NOD2 antagonist 1 (compound 32) is a potent and selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 inhibits Muramyl dipeptide (MDP) -induced IL-8 secretion in THP-1 cells and inhibits MDP-induced IL-6, IL-10, TNF-α release in PBMCs[1].
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CAS Number
[2411441-54-6]
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Molecular Formula
C26H26N4O3S
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Molecular Weight
474.57
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Smiles
O=C(NC1=CC2=C(CCC2)C=C1)CN3C4=CC=CC=C4N=C3CCNS(=O)(C5=CC=CC=C5)=O
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Target
NOD-like Receptor (NLR)
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Isoform
NOD2
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Purity
99.57
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Solubility
DMSO : 35.71 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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NOD2 antagonist 1 [CAS 2411441-54-6]
NOD2 antagonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.