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Nrf2 activator-10 [CAS 75483-04-4]

Nrf2 activator-10 [CAS 75483-04-4]

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QM-0132887-01

£231.03 GBP
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Product Details

  • Description

    Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.

  • CAS Number

    [75483-04-4]

  • Molecular Formula

    C13H12ClNO3

  • Molecular Weight

    265.69

  • Smiles

    O=C(C1=C(Cl)C2=C(C=CC=C2)N(C)C1=O)OCC

  • Target

    Apoptosis; Keap1-Nrf2

  • Purity

    98.65

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H317

  • Precautions

    H317
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Variant Variant total Quantity Price Variant total
100 mgQM-0132887-01
100 mgQM-0132887-01
£231.03/ea		 £0.00
£231.03/ea £0.00
10 mM - 1 mLQM-0132887-02
10 mM - 1 mLQM-0132887-02
£248.04/ea		 £0.00
£248.04/ea £0.00
250 mgQM-0132887-03
250 mgQM-0132887-03
£357.39/ea		 £0.00
£357.39/ea £0.00
1 gQM-0132887-04
1 gQM-0132887-04
£664.79/ea		 £0.00
£664.79/ea £0.00
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Nrf2 activator-10 [CAS 75483-04-4]

Nrf2 activator-10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.