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Nrf2 activator 18
Nrf2 activator 18
SKU:QM-0109944
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Product Details
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Description
Nrf2 activator 18 (Compound 11a) is an orally active activator for Keap1/Nrf2/HO-1 signaling pathway, that promotes the Nrf2 nuclear translocation, and enhances the antioxidant efficacy. Nrf2 activator 18 inhibits the release of IL-6 with an IC50 of 4.816 μM. Nrf2 activator 18 exhibits anti-inflammatory efficacy in mouse PM2.5-induced lung injury model[1].
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Molecular Formula
C23H24FN3O
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Molecular Weight
377.45
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Smiles
CN(C(C1=NN(C(C(C)(C)C)=C1)C2=CC=C(C=C2)F)=O)/C=C\C3=CC=CC=C3
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Target
Keap1-Nrf2
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Shipping Conditions
Room temperature
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Nrf2 activator 18
Nrf2 activator 18 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.