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Nrf2 activator-2 [CAS 2770448-53-6]

Nrf2 activator-2 [CAS 2770448-53-6]

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QM-0148755-01

£426.65 GBP
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Product Details

  • Description

    Nrf2 activator-2 (compound O15), a Osthole derivative, is a potent Nrf2 agonist with an EC50 of 2.9 μM in 293 T cells. Nrf2 activator-2 effectively inhibits the interaction between Keap1 and Nrf2, thus showing the activation effect on Nrf2. Nrf2 activator-2 shows a marked decrease in the level of ubiquitinated Nrf2 in cells[1].

  • CAS Number

    [2770448-53-6]

  • Molecular Formula

    C20H17BrO3

  • Molecular Weight

    385.25

  • Smiles

    CC1(CCC2=C3OC(C(C4=CC=CC=C4)=CC3=CC(Br)=C2O1)=O)C

  • Target

    Keap1-Nrf2

  • Concentration

    10mM

  • Purity

    99.2

  • Solubility

    DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0148755-01
5 mgQM-0148755-01
£426.65/ea		 £0.00
£426.65/ea £0.00
10 mM - 1 mLQM-0148755-02
10 mM - 1 mLQM-0148755-02
£464.31/ea		 £0.00
£464.31/ea £0.00
10 mgQM-0148755-03
10 mgQM-0148755-03
£652.64/ea		 £0.00
£652.64/ea £0.00
25 mgQM-0148755-04
25 mgQM-0148755-04
£1,279.58/ea		 £0.00
£1,279.58/ea £0.00
50 mgQM-0148755-05
50 mgQM-0148755-05
£1,995.21/ea		 £0.00
£1,995.21/ea £0.00
100 mgQM-0148755-06
100 mgQM-0148755-06
£3,162.83/ea		 £0.00
£3,162.83/ea £0.00
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Nrf2 activator-2 [CAS 2770448-53-6]

Nrf2 activator-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.