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Nrf2 activator-4 [CAS 2383016-68-8]
Nrf2 activator-4 [CAS 2383016-68-8]
SKU:QM-0148841-01
£238.32 GBP
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Product Details
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Description
Nrf2 activator-4 (Compound 20a) is a highly potent, orally active Nrf2 activator with an EC50 of 0.63 µM. Nrf2 activator-4 suppresses reactive oxygen species against oxidative stress in microglia. Nrf2 activator-4 effectively recovers the learning and memory impairment in a scopolamine-induced mouse model[1].
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CAS Number
[2383016-68-8]
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Molecular Formula
C23H24ClF3N2O3
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Molecular Weight
468.9
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Smiles
O=C(C1=CC=C(C=C1)OCC(N2CCN(CC2)C)=O)/C=C/C3=C(C=CC=C3)C(F)(F)F.Cl
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Target
Keap1-Nrf2; Reactive Oxygen Species (ROS)
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Concentration
10mM
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Purity
98.03
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Nrf2 activator-4 [CAS 2383016-68-8]
Nrf2 activator-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.