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Nrf2 activator-6 [CAS 2728780-74-1]
Nrf2 activator-6 [CAS 2728780-74-1]
SKU:QM-0067947
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Product Details
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Description
Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4) [1].
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CAS Number
[2728780-74-1]
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Molecular Formula
C31H37ClFN5O5
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Molecular Weight
614.11
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Smiles
OC([C@@](C)(CCC1)[C@@H]1C(N2[C@H](CN3C(CC4(C3)CC4)=O)C5=C(C(F)=CC(Cl)=C5CC2)OCC6=C7N(CCCC7)N=N6)=O)=O
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Target
Keap1-Nrf2; Quinone Reductase
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Purity
98.15
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Nrf2 activator-6 [CAS 2728780-74-1]
Nrf2 activator-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.