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Nrf2/HO-1 activator 2 [CAS 2883506-31-6]

Nrf2/HO-1 activator 2 [CAS 2883506-31-6]

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SKU:QM-0069368

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  • Description

    Nrf2/HO-1 activator 2 (compound 13m), difluoro-substituted derivative, is a potent Nrf2/HO-1 activator. Nrf2/HO-1 activator 2 has neuroprotective and antioxidant effects through the Nrf2/HO-1 pathway mediated by phosphorylation of ERK1/2, JNK, or Akt in PC12 cells. Nrf2/HO-1 activator 2 can be used in the research of Parkinson's disease (PD) [1].

  • CAS Number

    [2883506-31-6]

  • Molecular Formula

    C20H16F2O5

  • Molecular Weight

    374.33

  • Smiles

    O=C1C(C2=CC=C(F)C=C2F)=COC3=C1C4=C(CC(O)C(C)(C)O4)C(O)=C3

  • Target

    Akt; ERK; JNK; Keap1-Nrf2; Reactive Oxygen Species (ROS)

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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Nrf2/HO-1 activator 2 [CAS 2883506-31-6]

Nrf2/HO-1 activator 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.