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Nrf2/HO-1 activator 3
Nrf2/HO-1 activator 3
SKU:QM-0009667
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Product Details
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Description
Nrf2/HO-1 activator 3 (Compound C3a) is the activator for Nrf2 signaling pathway that promotes the Nrf2 translocation into nuclei and upregulates the expression of heme oxygenase-1 HO-1. Nrf2/HO-1 activator 3 inhibits the overespression of ROS and MDA in H2O2- or glucose-stimulated H9c2 cardiomyocytes, inhibits the cell viability and colony formation, thereby exhibiting antioxidant efficacy[1].
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Molecular Formula
C27H26N2O6
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Molecular Weight
474.51
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Smiles
O=C1NC2=C(C=CC=C2)C13N(C)C[C@H](C4=C(OC)C=CC=C4OC)[C@@H]3C(C5=CC=C(O)C(O)=C5)=O
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Target
Heme Oxygenase (HO) ; Keap1-Nrf2; Reactive Oxygen Species (ROS)
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Shipping Conditions
Room temperature
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Nrf2/HO-1 activator 3
Nrf2/HO-1 activator 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.