Nur77 modulator 3 [CAS 2097787-75-0]
Nur77 modulator 3 [CAS 2097787-75-0]
SKU:QM-0153300-01
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Product Details
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Description
Nur77 modulator 3 is a Nur77 modulator. Nur77 modulator 3 induces Nur77 expression, inhibits hepatic stellate cells (HSCs) activation, and reduces extracellular matrix (ECM) deposition. Nur77 modulator 3 enhances Nur77-denpendent autophagic flux and significantly inhibits the mTORC1 signaling pathway. Nur77 modulator 3 ameliorates HSCs activation, inflammation and hepatic fibrosis in vivo[1].
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CAS Number
[2097787-75-0]
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Molecular Formula
C17H16N4S
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Molecular Weight
308.4
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Smiles
S=C(N/N=C/C1=CNC2=CC=CC=C12)NC3=CC=C(C)C=C3
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Target
Atg8/LC3; Autophagy; mTOR; Nuclear Hormone Receptor 4A/NR4A; p62; TGF-beta/Smad
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Isoform
MTORC1; Nur77/NR4A1
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Purity
99.01
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Solubility
DMSO : 250 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Nur77 modulator 3 [CAS 2097787-75-0]
Nur77 modulator 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.