OGG1 activator-1
OGG1 activator-1
SKU:QM-0015658
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Product Details
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Description
OGG1 activator-1 (Compound 30) is a selective 8-oxoguanine DNA glycosylase-1 (OGG1) activator with an AC50 value of 0.58 μM. OGG1 activator-1 does not activate nor inhibit the key downstream repair enzyme APE1, and shows > 150-fold selectivity for the activation effect on OGG1. OGG1 activator-1 exhibits extremely high metabolic stability and almost no cytotoxicity. OGG1 activator-1 can be used for the study of oxidative stress-related diseases (such as neurodegenerative diseases, fibrotic diseases, cancer, inflammation, etc.) [1].
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Molecular Formula
C15H15N3O
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Molecular Weight
253.3
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Smiles
OC1=CC2=C(NC(C3=CC=CN=C3)=C2CCN)C=C1
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Target
DNA Glycosylase
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Shipping Conditions
Room temperature
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OGG1 activator-1
OGG1 activator-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.