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P-gp inhibitor 14 [CAS 2892571-47-8]
P-gp inhibitor 14 [CAS 2892571-47-8]
SKU:QM-0068611
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Product Details
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Description
P-gp inhibitor 14 (Compound 8a) is a high affinity P-gp inhibitor. P-gp inhibitor 14 reverses P-gp-mediated multidrug resistance (EC50=48.74 nM) . P-gp inhibitor 14 has a weak inhibitory effect on CYP3A4 activity[1].
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CAS Number
[2892571-47-8]
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Molecular Formula
C37H38N2O8
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Molecular Weight
638.71
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Smiles
COC1=CC2=C(CN(CC2)CCC3=CC=C(C=C3)N4CC5=CC(OC)=C6OCOC6=C5C7=C(C4)C=C(C8=C7OCO8)OC)C=C1OC
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Target
P-glycoprotein
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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P-gp inhibitor 14 [CAS 2892571-47-8]
P-gp inhibitor 14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.