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P-gp inhibitor 20
P-gp inhibitor 20
SKU:QM-0110971
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Product Details
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Description
P-gp inhibitor 20 (compound H27) is a low cytotoxicity P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 20 inhibits the efflux function of P-gp in a dose-dependent manner (without affecting the expression of P-gp), thereby reversing the multidrug resistance (MDR) of MCF-7/ADR cells, with an IC50 value of 46.6 nM. P-gp inhibitor 20 can be used for cancer research[1].
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Molecular Formula
C30H28N4O3Se
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Molecular Weight
571.53
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Smiles
O=C(C1=CC=CC([Se]C2=CNC3=CC=C(C4=CN(C)N=C4)C=C32)=C1)N5CCC6=CC(OC)=C(OC)C=C6C5
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Target
P-glycoprotein
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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P-gp inhibitor 20
P-gp inhibitor 20 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.