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P-gp inhibitor 27
P-gp inhibitor 27
SKU:QM-0093482
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Product Details
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Description
P-gp inhibitor 27 (Compound D2) is an inhibitor for P-glycoprotein (P-gp), that downregulates the expression of P-gp and MRP1, increases the Rh123 accumulation in A2780/T cell, and reverses multidrug resistance to Paclitaxel (EC50 is 88 nM) and Cisplatin (HY-17394).
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Molecular Formula
C25H25N3O4
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Molecular Weight
431.48
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Smiles
COC1=CC(C2=CC=C(CNC(C3=CN(C)C4=C3C=CC=C4)=O)N=C2)=CC(OC)=C1OC
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Target
P-glycoprotein
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Shipping Conditions
Room temperature
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P-gp inhibitor 27
P-gp inhibitor 27 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.