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P-gp inhibitor 4 [CAS 2652001-05-1]
P-gp inhibitor 4 [CAS 2652001-05-1]
SKU:QM-0066831
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Product Details
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Description
P-gp inhibitor 4 (Compound 8b) is a selective P-glycoprotein modulator with an EC50 of 94 nM. P-gp inhibitor 4 increases agent transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells[1].
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CAS Number
[2652001-05-1]
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Molecular Formula
C38H38N2O8S2
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Molecular Weight
714.85
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Smiles
COC1=CC=C(C=C1)S(=O)(N(S(=O)(C2=CC=C(C=C2)OC)=O)C3=CC=C(C=C3)C4=CC=C(C=C4)CN5CCC6=CC(OC)=C(C=C6C5)OC)=O
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Target
P-glycoprotein
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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P-gp inhibitor 4 [CAS 2652001-05-1]
P-gp inhibitor 4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.