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P-gp modulator-4

P-gp modulator-4

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SKU:QM-0095131

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  • Description

    P-gp modulator-4 (compound 4c) inhibits the efflux function of P-glycoprotein (P-gp). P-gp modulator-4 shows multidrug resistance (MDR) in cancer reversal activity (IC50 of Paclitaxel = 8.80, reversal fold = 211.8).

  • Molecular Formula

    C40H68N2O6

  • Molecular Weight

    672.98

  • Smiles

    CC(C)(O)[C@H](O1)CC[C@@]1(C)[C@@]2([H])CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](NC(CC6CN(C(OC(C)(C)C)=O)C6)=O)CC[C@]5(C)[C@@]4([H])C[C@@H](O)[C@@]32[H]

  • Target

    P-glycoprotein

  • Shipping Conditions

    Room temperature

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P-gp modulator-4

P-gp modulator-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.