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P2X3 antagonist 34 [CAS 2417288-67-4]

P2X3 antagonist 34 [CAS 2417288-67-4]

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QM-0145312-01

£489.83 GBP
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Product Details

  • Description

    P2X3 antagonist 34 is a potent, selective and orally active P2X3 homotrimeric receptor antagonist with IC50s of 25 nM, 92 nM and 126 nM for human P2X3, rat P2X3 and guinea pig P2X3 receptors, respectively. P2X3 antagonist 34 is less active against human, rat and guinea pig P2X2/3 heterotrimeric receptors. P2X3 antagonist 34 has strong anti-tussive effect[1].

  • CAS Number

    [2417288-67-4]

  • Molecular Formula

    C24H26F2N4O3

  • Molecular Weight

    456.49

  • Smiles

    O=C(OC)N1C[C@@H](CCC1)CC2=C(N=C3C=C(C=CN32)C)C4=C(C=C(C=C4F)C(NC)=O)F

  • Target

    P2X Receptor

  • Isoform

    P2X3 Receptor

  • Purity

    99.44

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C (Powder, protect from light)

  • Shipping Conditions

    Blue Ice
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Variant Variant total Quantity Price Variant total
5 mgQM-0145312-01
5 mgQM-0145312-01
£489.83/ea		 £0.00
£489.83/ea £0.00
10 mM - 1 mLQM-0145312-02
10 mM - 1 mLQM-0145312-02
£527.50/ea		 £0.00
£527.50/ea £0.00
10 mgQM-0145312-03
10 mgQM-0145312-03
£803.30/ea		 £0.00
£803.30/ea £0.00
50 mgQM-0145312-04
50 mgQM-0145312-04
£2,183.54/ea		 £0.00
£2,183.54/ea £0.00
100 mgQM-0145312-05
100 mgQM-0145312-05
£3,313.49/ea		 £0.00
£3,313.49/ea £0.00
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P2X3 antagonist 34 [CAS 2417288-67-4]

P2X3 antagonist 34 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.