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P2X3 antagonist 38 [CAS 2545974-71-6]

P2X3 antagonist 38 [CAS 2545974-71-6]

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SKU:QM-0070743

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  • Description

    P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].

  • CAS Number

    [2545974-71-6]

  • Molecular Formula

    C22H25F3N6O3

  • Molecular Weight

    478.47

  • Smiles

    CCOC(N([C@@H]1C(C2=CC=C(C=C2)C)=NN(C1)C(N[C@@H](C3=CN=C(C(F)(F)F)N=C3)C)=O)C)=O

  • Target

    P2X Receptor

  • Isoform

    P2X3 Receptor

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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P2X3 antagonist 38 [CAS 2545974-71-6]

P2X3 antagonist 38 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.