Name: P2Y14R antagonist 1 [CAS 2728291-29-8]
Brand: QuantiMol
SKU: QM-0106132-01
Price: 200.66 GBP
Availability: InStock

Product Details

Description
P2Y14R antagonist 1 (compound I-17) is a selective P2Y14R antagonist with an IC50 of 0.6 nM. It exhibits potent P2Y14R antagonistic activity, both in vitro and in vivo efficacy, and favorable pharmacokinetic profiles. P2Y14R antagonist 1 reduces the release of inflammatory factors and cell pyroptosis through the NOD-like receptor family pyrin domain-containing 3 (NLRP3) /gasdermin D (GSDMD) signaling pathway. P2Y14R antagonist 1 holds promise for research in the field of acute gouty arthritis[1].
CAS Number
[2728291-29-8]
Molecular Formula
C15H12BrN3O2
Molecular Weight
346.18
Smiles
O=C(NC1=CC2=C(C=C1)N=CN2)COC3=CC=C(C=C3)Br
Target
NOD-like Receptor (NLR) ; P2Y Receptor
Isoform
NLRP3; P2Y1 Receptor; P2Y12 Receptor; P2Y14 Receptor; P2Y2 Receptor; P2Y6 Receptor
Purity
98.76
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0106132-01	5 mgQM-0106132-01 £200.66/ea	£0.00	Quantity	£200.66/ea	£0.00

10 mM - 1 mLQM-0106132-02	10 mM - 1 mLQM-0106132-02 £215.24/ea	£0.00	Quantity	£215.24/ea	£0.00

10 mgQM-0106132-03	10 mgQM-0106132-03 £288.14/ea	£0.00	Quantity	£288.14/ea	£0.00

25 mgQM-0106132-04	25 mgQM-0106132-04 £527.50/ea	£0.00	Quantity	£527.50/ea	£0.00

50 mgQM-0106132-05	50 mgQM-0106132-05 £815.45/ea	£0.00	Quantity	£815.45/ea	£0.00

100 mgQM-0106132-06	100 mgQM-0106132-06 £1,267.43/ea	£0.00	Quantity	£1,267.43/ea	£0.00

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P2Y14R antagonist 1 [CAS 2728291-29-8]

P2Y14R antagonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.