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P38α inhibitor 6
P38α inhibitor 6
SKU:QM-0007948
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Product Details
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Description
P38α inhibitor 6 (compound 19) is a p38α inhibitor with the IC50 of 0.68 μM. p38α inhibitor 6 induces cell apoptosis and arrests cell cycle at G0 and G2/M phase. p38α inhibitor 6 decreases the TNF-α concentration as well as increased the expression of tumor suppressor gene p53, Bax/BCL-2 ratio and caspase 3/7[1].
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Molecular Formula
C25H19BrN6O
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Molecular Weight
499.36
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Smiles
BrC1=CC=CC(N2C(N=CN=C3NC4=CC=C(C(NC5=CC=C(C)C=C5)=O)C=C4)=C3C=N2)=C1
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Target
Apoptosis; Bcl-2 Family; Caspase; MDM-2/p53; p38 MAPK
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Shipping Conditions
Room temperature
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P38α inhibitor 6
P38α inhibitor 6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.