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P62-RNF168 agonist-1 [CAS 2765180-17-2]

P62-RNF168 agonist-1 [CAS 2765180-17-2]

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QM-0150650-01

£467.96 GBP
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Product Details

  • Description

    P62-RNF168 agonist-1 (compound 5a) is a low cytotoxicity P62-RNF168 agonist that enhances the interaction between P62 and RNF168. P62-RNF168 agonist-1 induces a reduction in H2A ubiquitination mediated by RNF168 and impairs homologous recombination-mediated DNA repair. P62-RNF168 agonist-1 also inhibits the growth of xenograft tumors in mice in a dose-dependent manner[1].

  • CAS Number

    [2765180-17-2]

  • Molecular Formula

    C19H19N7O3

  • Molecular Weight

    393.4

  • Smiles

    NC1=C2C(C=CC(C3=CN(C4=CC(OC)=C(C(OC)=C4)OC)N=N3)=C2)=NC(N)=N1

  • Target

    Apoptosis; E1/E2/E3 Enzyme; p62

  • Purity

    98.62

  • Solubility

    DMSO : ≥ 60 mg/mL

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
10 mM - 1 mLQM-0150650-01
10 mM - 1 mLQM-0150650-01
£467.96/ea		 £0.00
£467.96/ea £0.00
5 mgQM-0150650-02
5 mgQM-0150650-02
£533.57/ea		 £0.00
£533.57/ea £0.00
10 mgQM-0150650-03
10 mgQM-0150650-03
£775.36/ea		 £0.00
£775.36/ea £0.00
25 mgQM-0150650-04
25 mgQM-0150650-04
£1,427.81/ea		 £0.00
£1,427.81/ea £0.00
50 mgQM-0150650-05
50 mgQM-0150650-05
£1,980.63/ea		 £0.00
£1,980.63/ea £0.00
100 mgQM-0150650-06
100 mgQM-0150650-06
£2,752.16/ea		 £0.00
£2,752.16/ea £0.00
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P62-RNF168 agonist-1 [CAS 2765180-17-2]

P62-RNF168 agonist-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.