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PAR4 antagonist 8
PAR4 antagonist 8
SKU:QM-0106268
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Product Details
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Description
PAR4 antagonist 8 (Compound 20f) is an effective, orally active, and selective PAR4 antagonist with an IC50 value of 15.32 nM. PAR4 antagonist 8 exhibits favorable pharmacokinetic properties. PAR4 antagonist 8 not only effectively inhibits human platelet aggregation induced by PAR4 agonists (IC50 = 6.39 nM) but also inhibits mouse platelet aggregation. PAR4 antagonist 8 can be used in antithrombotic research[1].
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Molecular Formula
C28H19F2N5O4S
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Molecular Weight
559.54
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Smiles
COC1=NC2=CC(C)=CC(C3=NC4=C(S3)C(C[C@@H](O5)COC(NC6=CC(F)=CC(C#N)=C6)=O)=C5C(F)=C4)=C2C=N1
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Target
Protease Activated Receptor (PAR)
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Shipping Conditions
Room temperature
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PAR4 antagonist 8
PAR4 antagonist 8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.