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PDE4D inhibitor 1
PDE4D inhibitor 1
SKU:QM-0011390
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Product Details
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Description
PDE4-IN-1 is a PDE4 inhibitor with high potency (IC50 : 8.6 nM) and selectivity over other PDE subtypes. PDE4-IN-1 inhibits the release of inflammatory cytokines and chemokines. PDE4-IN-1 greatly restores impaired cAMP-CREB signaling pathway. PDE4-IN-1 inhibits proliferation and promotes differentiation to reverse the formation of psoriasis[1].
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Molecular Formula
C25H25F2NO7
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Molecular Weight
489.47
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Smiles
COC([C@H]1C[C@@H](OC2=C3OC(C4=CC=C(OC(F)F)C(OCC5CC5)=C4)=CC3=CC=C2O)CN1)=O
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Target
CXCR; Interleukin Related; Phosphodiesterase (PDE) ; TNF Receptor
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Isoform
PDE1; PDE10; PDE2; PDE3; PDE4; PDE5; PDE7; PDE8; PDE9
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Shipping Conditions
Room temperature
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PDE4D inhibitor 1
PDE4D inhibitor 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.