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PDGFRα kinase inhibitor 3
PDGFRα kinase inhibitor 3
SKU:QM-0011375
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Product Details
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Description
PDGFRα kinase inhibitor 3 (Compound L7) is a highly potent inhibitor targeting the PDGFRαD842V kinase with IC50s values of 23.8 nM and 2.1 nM in biochemical and cellular assays, respectively. PDGFRα kinase inhibitor 3 binds to the ATP-binding pocket of PDGFRαD842V to block its downstream signaling pathways and inhibit kinase activity. PDGFRα kinase inhibitor 3 can be used for gastrointestinal stromal tumors (GISTs) study[1].
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Molecular Formula
C23H23N5O
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Molecular Weight
385.46
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Smiles
C1(N2C=NC3=C2C=C4C=C3)=CC=C5C(C(N6CCC(CC6)NCCO4)=CC=C5)=N1
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Target
PDGFR
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Shipping Conditions
Room temperature
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PDGFRα kinase inhibitor 3
PDGFRα kinase inhibitor 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.