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PI3K/mTOR Inhibitor-11 [CAS 2845104-25-6]
PI3K/mTOR Inhibitor-11 [CAS 2845104-25-6]
SKU:QM-0150593-01
£727.97 GBP
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Product Details
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Description
PI3K/mTOR Inhibitor-11 is an orally active PI3K/mTOR inhibitor (IC50: 3.5, 4.6, and 21.3 nM for PI3Kα, PI3Kδ, and mTOR) . PI3K/mTOR Inhibitor-11 regulates the PI3K/AKT/mTOR signaling pathway by inhibiting the phosphorylation of AKT and S6 proteins. PI3K/mTOR Inhibitor-11 can be used in the research of cancers[1].
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CAS Number
[2845104-25-6]
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Molecular Formula
C27H21N7
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Molecular Weight
443.5
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Smiles
CC(C1=NC=C(N2C(C)=NC3=C2C4=CC(C5=CN=C(NC=C6)C6=C5)=CC=C4N=C3)C=C1)(C)C#N
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Target
MTOR; PI3K
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Isoform
PI3Kα; PI3Kδ
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Concentration
10mM
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Purity
99.65
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Solubility
DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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PI3K/mTOR Inhibitor-11 [CAS 2845104-25-6]
PI3K/mTOR Inhibitor-11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.