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PKM2 activator 6
PKM2 activator 6
SKU:QM-0072354
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Product Details
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Description
PKM2 activator 6 (Compound Z10) is a PKM2 activator and PDK1 inhibitor (KD: 121 and 19.6 μM respectively) . PKM2 activator 6 induces colorectal cell apoptosis, and inhibits cell proliferation and migration . PKM2 activator 6 inhibits glycolysis. PKM2 activator 6 inhibits proliferation of DLD-1, HCT-8, HT-29, MCF-10A cells (IC50: 10.04, 2.16, 3.57, 66.39 μM) [1].
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Molecular Formula
C29H31NO10S2
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Molecular Weight
617.69
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Smiles
O=C(OC)C(CS[C@@H](C(C1=O)=CC(C2=C1C(O)=CC=C2O)=O)C/C=C(C)\C)NC(C3=CC(S(=O)(C)=O)=CC=C3OC)=O
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Target
PDK-1; Pyruvate Kinase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PKM2 activator 6
PKM2 activator 6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.