PPARδ agonist 10 [CAS 685139-10-0]
PPARδ agonist 10 [CAS 685139-10-0]
SKU:QM-0091759-01
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Product Details
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Description
PPARδ agonist 10 (compound 7) is an orally active, selective, and partial agonist of PPARδ, with EC50 values of 0.053 μM and 0.30 µM for hPPARδ (LBD) -GAL4 and mPPARδ, respectively. PPARδ agonist 10 is a partial PPARδ agonist in transactivation assay but a full agonist on free fatty acids (FFA) oxidation in muscle cells both in vitro and in vivo. PPARδ agonist 10 can be used for dyslipidemia research[1].
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CAS Number
[685139-10-0]
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Molecular Formula
C23H17Br2ClO3S
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Molecular Weight
568.71
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Smiles
O=C(COC1=CC=C(C=C1Cl)SC/C=C(C2=CC=C(C=C2)Br)/C3=CC=C(C=C3)Br)O
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Target
PPAR
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Isoform
PPARδ
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Solubility
10 mM in Ethanol
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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PPARδ agonist 10 [CAS 685139-10-0]
PPARδ agonist 10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.