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PPARα/δ agonist 3 [CAS 3050611-33-8]
PPARα/δ agonist 3 [CAS 3050611-33-8]
SKU:QM-0008541
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Product Details
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Description
PPARα/δ agonist 3 (Compound 8) is the orally active agonist for PPAR, that activates PPARα, PPARδ and PPARγ with EC50s of 5.6, 3.4 and 1278 nM, respectively. PPARα/δ agonist 3 exhibits anticholestatic activity in mouse ANIT- or CDCA -induced cholestatic liver disease models[1].
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CAS Number
[3050611-33-8]
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Molecular Formula
C23H25F3N2O4
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Molecular Weight
450.45
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Smiles
CC(C)(OC1=C(C)C=C(CN2CCN(C3=CC=C(C(F)(F)F)C=C3)C2=O)C=C1C)C(O)=O
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Target
PPAR
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Isoform
PPARα; PPARγ; PPARδ
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Shipping Conditions
Room temperature
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PPARα/δ agonist 3 [CAS 3050611-33-8]
PPARα/δ agonist 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.