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PPL agonist-1 [CAS 3040997-52-9]
PPL agonist-1 [CAS 3040997-52-9]
SKU:QM-0095449
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Product Details
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Description
PPL agonist-1 is a highly selective Periplakin (PPL) agonist that increases cAMP levels by regulating PPL, thereby enhancing MITF expression and promoting melanin synthesis. Furthermore, PPL agonist-1 facilitates melanin production by regulating tryptophan metabolism. Compared to Ruxolitinib , PPL agonist-1 demonstrates superior efficacy. PPL agonist-1 holds potential for research into vitiligo treatment[1].
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CAS Number
[3040997-52-9]
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Molecular Formula
C25H22FN5O4S
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Molecular Weight
507.54
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Smiles
CC1=C(F)C=CC(C2=CC=C([C@@H](NC3=NC(NS(=O)(C4=CC([N+]([O-])=O)=CC=C4)=O)=CC=N3)C)C=C2)=C1
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Target
Microtubule/Tubulin; Tyrosinase
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Shipping Conditions
Room temperature
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PPL agonist-1 [CAS 3040997-52-9]
PPL agonist-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.