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PRMT5-targeted fluorescent ligand-1

PRMT5-targeted fluorescent ligand-1

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SKU:QM-0009453

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  • Description

    PRMT5-targeted fluorescent ligand-1 (Compound 7) is a PRMT5-targeted fluorescent ligand, that inhibits PRMT5 with an IC50 of 29.39 nM. PRMT5-targeted fluorescent ligand-1 exhibits cell imaging activity, that exhibits good fluorescence signal in MCF-7 with an IC50 of 29 nM. PRMT5-targeted fluorescent ligand-1 induces apoptosis. PRMT5-targeted fluorescent ligand-1 exhibits a maximal excitation wavelength of 438 nm and a maximal emission wavelength of 550 nm[1].

  • Molecular Formula

    C43H47N7O5

  • Molecular Weight

    741.88

  • Smiles

    O=C1N(C2CCN(CC(N3CC(NC4=CC5=C(C=C4)CCN(C[C@@H](O)CN6CC7=C(C=CC=C7)CC6)C5=O)C3)=O)CC2)C(C8=CC=C(N)C9=CC=CC1=C89)=O

  • Target

    Apoptosis; Fluorescent Dye; Histone Methyltransferase

  • Shipping Conditions

    Room temperature

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PRMT5-targeted fluorescent ligand-1

PRMT5-targeted fluorescent ligand-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.