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Progranulin modulator-1 [CAS 2641013-11-6]
Progranulin modulator-1 [CAS 2641013-11-6]
SKU:QM-0070732
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Product Details
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Description
Progranulin modulator-1 (Compound 60) is an orally active enhancer of progranulin (PGRN) secretion. Progranulin modulator-1 enhances the potency of BV-2 cell to increase PGRN levels, has inhibitory effect on hERG and Low cytotoxicity, the PGRN EC50 and hERG IC50 were 83 and 3100 nM, respectively[1].
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CAS Number
[2641013-11-6]
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Molecular Formula
C21H21F2N3O
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Molecular Weight
369.41
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Smiles
FC1=CC=C(C=C1)[C@@H]2N(C3=N[C@H](C4(CNC4)F)CO3)CCC5=CC=CC=C52
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Target
TNF Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Progranulin modulator-1 [CAS 2641013-11-6]
Progranulin modulator-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.