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PROTAC CRBN ligand-2
PROTAC CRBN ligand-2
SKU:QM-0101404
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Product Details
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Description
PROTAC CRBN ligand-2 (12) is a Biguanide-PROTAC derivative, with an EC50 of 0.15 mM in KP4 cells. PROTAC CRBN ligand-2 (12) demonstrates the ability to alter levels of mitochondrial proteins, notably complexes I and IV[1].
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Molecular Formula
C33H30N8O8
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Molecular Weight
666.64
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Smiles
N=C(NC(NCC1=CC=C(C=C1)C#CC2=CC=C(C=C2)NC(COC3=CC=CC4=C3C(N(C4=O)C5CCC(NC5=O)=O)=O)=O)=N)N.O=CO
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Target
Ligands for E3 Ligase
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Isoform
Cereblon
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PROTAC CRBN ligand-2
PROTAC CRBN ligand-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.