Proteasome inhibitor IX [CAS 856849-35-9]
Proteasome inhibitor IX [CAS 856849-35-9]
SKU:QM-0112495-01
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Product Details
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Description
Proteasome inhibitor IX (PS-IX; AM114) is a Chalcone derivative and a chymotrypsin-like activity of the 20S proteasome inhibitor with an IC50 value of ~1 μM. Proteasome inhibitor IX exhibits HCT116 p53+/+ cells growth inhibitory activity with an IC50 value of 1.49 μM. Proteasome inhibitor IX has potent anticancer activity[1][2].
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CAS Number
[856849-35-9]
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Molecular Formula
C20H21B2NO5
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Molecular Weight
377.01
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Smiles
O=C(/C(CN(C)C/1)=C\C2=CC=C(B(O)O)C=C2)C1=C/C3=CC=C(B(O)O)C=C3
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Target
Proteasome
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Purity
99.43
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Solubility
DMSO : 6.25 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302-H315-H319
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Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
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Proteasome inhibitor IX [CAS 856849-35-9]
Proteasome inhibitor IX is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.