RAS inhibitor Abd-7 [CAS 2351843-48-4]
RAS inhibitor Abd-7 [CAS 2351843-48-4]
SKU:QM-0140688-01
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Product Details
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Description
RAS inhibitor Abd-7, a potent RAS-binding compound (Kd=51 nM), is a RAS-effector protein-protein interaction (PPI) inhibitor. RAS inhibitor Abd-7 interacts with RAS inside the cells, prevents RAS-effector interactions and inhibits endogenous RAS-dependent signaling. RAS inhibitor Abd-7 impairs the PPI of various mutant KRAS proteins with PI3K, CRAF and RALGDS as well as NRAS Q61H and HRAS G12V[1].
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CAS Number
[2351843-48-4]
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Molecular Formula
C23H25N3O3
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Molecular Weight
391.46
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Smiles
COC1=NC(C2=C3C(OCCO3)=CC=C2)=CC=C1NC4=CC=C(CN(C)C)C=C4
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Target
Ras
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Purity
99.57
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Solubility
DMSO : 125 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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RAS inhibitor Abd-7 [CAS 2351843-48-4]
RAS inhibitor Abd-7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.