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RIP1 kinase inhibitor 9
RIP1 kinase inhibitor 9
SKU:QM-0153543
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Product Details
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Description
RIP1 kinase inhibitor 9 (compound SY-1) is a selective RIP kinase inhibitor. RIP1 kinase inhibitor 9 effectively suppresses the central inflammatory response induced by epilepsy. RIP1 kinase inhibitor 9 inhibits Z-VAD-FMK -induced necroptosis in HT-29 cells with an EC50 of 7.04 nM[1].
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Molecular Formula
C25H21N3O3
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Molecular Weight
411.45
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Smiles
CN1C([C@H](COC2=CC=CC=C21)NC(C3=CC4=C(NC=C4C5=CC=CC=C5)C=C3)=O)=O
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Target
Necroptosis; RIP kinase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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RIP1 kinase inhibitor 9
RIP1 kinase inhibitor 9 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.