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RNF5 inhibitor inh-02 [CAS 324579-65-9]

RNF5 inhibitor inh-02 [CAS 324579-65-9]

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QM-0141030-01

£339.17 GBP
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Product Details

  • Description

    RNF5 inhibitor inh-02 is a potent inhibitor of E3 ubiquitin ligase RNF5/RMA1. RNF5 inhibitor inh-02 rescues F508del-CFTR function in F508del-CFTR-expressing immortalized cells (CFBE41o⁻, EC50 = 2.6 μM; FRT, EC 50 = 2.2 μM) . RNF5 inhibitor inh-02 increases LC3IIB expression and autophagic vacuole number via reducing ATG4B ubiquitylation and promotes cell motility. RNF5 inhibitor inh-02 can be used for the study of cystic fibrosis[1].

  • CAS Number

    [324579-65-9]

  • Molecular Formula

    C23H20N4S

  • Molecular Weight

    384.5

  • Smiles

    CC1=NS/C(N1CC2=CC=CC=C2)=N\C(C3=CC=CC=C3)=N\C4=CC=CC=C4

  • Target

    Atg8/LC3; E1/E2/E3 Enzyme

  • Purity

    99.91

  • Solubility

    DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302, H318

  • Precautions

    H302, H318
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Variant Variant total Quantity Price Variant total
5 mgQM-0141030-01
5 mgQM-0141030-01
£339.17/ea		 £0.00
£339.17/ea £0.00
10 mM - 1 mLQM-0141030-02
10 mM - 1 mLQM-0141030-02
£367.12/ea		 £0.00
£367.12/ea £0.00
10 mgQM-0141030-03
10 mgQM-0141030-03
£551.80/ea		 £0.00
£551.80/ea £0.00
25 mgQM-0141030-04
25 mgQM-0141030-04
£1,116.77/ea		 £0.00
£1,116.77/ea £0.00
50 mgQM-0141030-05
50 mgQM-0141030-05
£1,870.07/ea		 £0.00
£1,870.07/ea £0.00
100 mgQM-0141030-06
100 mgQM-0141030-06
£3,188.34/ea		 £0.00
£3,188.34/ea £0.00
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RNF5 inhibitor inh-02 [CAS 324579-65-9]

RNF5 inhibitor inh-02 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.