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RORγt agonist 1 [CAS 2377378-89-5]
RORγt agonist 1 [CAS 2377378-89-5]
SKU:QM-0060828
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Product Details
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Description
RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist with an EC50 of 20.8 nM. RORγt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORγt agonist 1 is a potential candidate of RORγt agonist for cancer immunotherapy[1].
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CAS Number
[2377378-89-5]
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Molecular Formula
C24H17F6NO5S
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Molecular Weight
545.45
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Smiles
FC1=CC(OC(F)F)=CC(C2=CC=C(CC(CC(O)=O)N3S(C4=CC(C(F)(F)F)=CC=C4)(=O)=O)C3=C2)=C1
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Target
ROR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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RORγt agonist 1 [CAS 2377378-89-5]
RORγt agonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.