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RORγt agonist 2 [CAS 2663787-92-4]
RORγt agonist 2 [CAS 2663787-92-4]
SKU:QM-0065114
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Product Details
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Description
RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17) [1].
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CAS Number
[2663787-92-4]
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Molecular Formula
C30H30F3N3O4S
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Molecular Weight
585.64
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Smiles
CC(C1N(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C(N[C@H](C4=CC=C(C=C4)S(CC)(=O)=O)CC#N)=O)C=C3OC1)C
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Target
ROR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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RORγt agonist 2 [CAS 2663787-92-4]
RORγt agonist 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.