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RORγt Inverse agonist 10 [CAS 2413986-35-1]

RORγt Inverse agonist 10 [CAS 2413986-35-1]

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QM-0144491-01

£902.93 GBP
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Product Details

  • Description

    RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R[1]

  • CAS Number

    [2413986-35-1]

  • Molecular Formula

    C25H26F6N6O3

  • Molecular Weight

    572.5

  • Smiles

    C[C@H](N(C(CC(C(F)(F)F)C(F)(F)F)=O)CC1)C[C@H]1OC2=C(C)C(NC(C3=CN=C(C)C=C3)=O)=CN4C2=NC=N4

  • Target

    ROR

  • Isoform

    RORγ

  • Purity

    99.13

  • Solubility

    DMSO : ≥ 100 mg/mL

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture and light)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0144491-01
5 mgQM-0144491-01
£902.93/ea		 £0.00
£902.93/ea £0.00
10 mM - 1 mLQM-0144491-02
10 mM - 1 mLQM-0144491-02
£1,124.06/ea		 £0.00
£1,124.06/ea £0.00
10 mgQM-0144491-03
10 mgQM-0144491-03
£1,430.24/ea		 £0.00
£1,430.24/ea £0.00
25 mgQM-0144491-04
25 mgQM-0144491-04
£2,873.66/ea		 £0.00
£2,873.66/ea £0.00
50 mgQM-0144491-05
50 mgQM-0144491-05
£4,443.44/ea		 £0.00
£4,443.44/ea £0.00
100 mgQM-0144491-06
100 mgQM-0144491-06
£7,078.77/ea		 £0.00
£7,078.77/ea £0.00
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RORγt Inverse agonist 10 [CAS 2413986-35-1]

RORγt Inverse agonist 10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.